标题:
First Report of an Outbreak of Mycoplasmal Round Pneumonia in an Adult Population: A Case Series
讲者:
文文
单位:
南京军区福州总医院
播放:
1109
论文摘要:
Background: Mycoplasmal pneumonia has been identified as one of the most common types of community acquired pneumonia in Chinese adults. However, previous reports confirm that it seldom manifests as round or spherical pneumonia. Mycoplasma pneumoniae has been implicated in the etiology of round pneumonia only once before (in a pediatric population) and has never previously been identified as the cause of adult round pneumonia. Here, we report an extremely rare outbreak of mycoplasmal round pneumonia in an adult population.
Methods: We abstracted and analysed epidemiological, clinical, imageological and laboratory data from a case series of an outbreak of round pneumonia caused by MP in the dormitory of a military hospital in China. Cases were confirmed as testing anti-MP antibodies with dynamic increase in titer.
Results: All 12 subjects were mildly symptomatic or asymptomatic and no sign except for fever on physical examination with spherical mass (es) by Chest CT scan. Chest radiological appearance revealed single in 3 cases and multiple in 9 round-shaped consolidations ranged in size from 0.2-2.9 cm. Most of patients had normal blood cell counts, erythrocyte sedimentation rate ( ESR ) and C reactive protein (CRP). Four-fold increase in the MP antibody titer in the paired sera was observed in all 12 patients. Negative results for 25 pathogens including M. pneumoniae in a polymerase chain reaction based assay performed on nasopharyngeal swabs. Subjects were either given moxifloxacin (antibiotic therapy) or symptomatic treatment. Complete resolution of round pneumonia lesions was achieved within 4 weeks in 91% of the patients.
Conclusion: This round pneumonia of the adult group caused by MP and should be included in future in the differential diagnosis of multiple pulmonary nodules in order to enable accurate clinical identification of disease and successful treatment and resolution.